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Big NIH winners in Massachusetts

What does it take to get a new, large National Institutes of Health (NIH) research grant in these lean times?

William Gregory Feero

Dr. Feero is currently a special advisor to the Director for Genomic Medicine for the Genomic Healthcare Branch, National Human Genome Research Institute (NHGRI). His interests include the development of electronic, health-record-based tools for genomics in clinical practice, and genomics education for the health professions. Dr. Feero graduated from Pennsylvania State University with a major in molecular biology and a minor in chemistry.

Dan E. Arking

My research focuses on cardiovascular genomics and aging, with the primary goal of identifying and characterizing genetics variants underlying complex human disease. Traditional approaches to identify genes involved in cardiovascular disease have relied upon screening candidate genes or family-based linkage studies in families with rare monogenic forms of disease. Given the limited success of these approaches to identify genes contributing to common disease, our group has pioneered the use of genome-wide association studies.

Craig Benham

The Genome and Biomedical Sciences Facility, a $90 million building at UC Davis, houses the UC Davis Center for Genomics and other research groups in biomedical sciences. Leading the center is Associate Director Craig Benham, an expert in DNA structure and bioinformatics. Benham believes that working out the information content of genome sequences and how their genes are regulated together are the next challenges in genomic science.

Bradley E. Aouizerat

Dr. Aouizerat's research is centered on understanding the quantitative genetics (genomics) of common human disease. He is interested in accelerating the translation of discoveries in basic science genetics (the bench) to clinical practice (the bedside). Of particular interest to his lab is the role of common genetic variations in dyslipidemia, a risk factor for cardiovascular diseases. Currently, he is investigating four clinical populations with discrete cardiovascular diseases: familial combined hyperlipidemia, hypoalphalipoproteinemia, hyperalphalipoproteinmia and normolipidemic controls.

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