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The Markingson Files

The Markingson Files: University of Minnesota dallies on clinical trial documentation

A candid email from a university publicist sheds some, but not enough, light on why the university won't provide documents from a controversial Seroquel clinical study.

The Markingson Files: Conflicts of interest in clinical trials should be transparent

It can be uncomfortable asking people about their finances. In journalism, though, there is an obligation not only to ask, but to ask for proof — especially with clinical trials.

The Markingson Files: Why health writers should track the money behind medical studies

One of the biggest oversights a health writer can make is to cover a scientific study and not talk about its funders. William Heisel examines what can happen when a study's funding is overlooked.

The Markingson Files: Can pressure to recruit patients subvert a clinical trial?

Bioethicist and writer Carl Elliott used many documents to piece together the story of how a research team desperate for patients helped create a pipeline for clinical trial participants by setting up a psychiatric ward. Here's how he did it.

The Markingson Files: Can a mentally ill patient consent to a clinical trial?

Documents behind a controversial Seroquel drug trial raise serious questions about how patients with mental disorders are judged competent to participate in clinical trials all over the world.

The Markingson Files: University can't control the story of a clinical trial suicide

A war of words has erupted at the University of Minnesota campus over bioethics writer and UM professor Carl Elliott’s reporting into the suicide of a schizophrenic patient enrolled in a clinical trial.

Q&A with Dr. Carl Elliott, Part 2: Finding fault with his own university after patient's death

Dr. Carl Elliott, a University of Minnesota bioethicist, has spent much of the last two years doggedly pursuing the case of Dan Markingson, a 26-year-old who killed himself during a UM clinical trial meant to prove the superiority of AstraZeneca’s Seroquel over its competitors.

Q&A with Dr. Carl Elliott: Making patient protection a priority for clinical trials

Dr. Carl Elliott is a brave man. A bioethicist with an MD, Elliott took on powerful interests at his own university on behalf of a woman he barely knew and a patient he could not save.

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