Bradley E. Aouizerat
Dr. Aouizerat's research is centered on understanding the quantitative genetics (genomics) of common human disease. He is interested in accelerating the translation of discoveries in basic science genetics (the bench) to clinical practice (the bedside). Of particular interest to his lab is the role of common genetic variations in dyslipidemia, a risk factor for cardiovascular diseases. Currently, he is investigating four clinical populations with discrete cardiovascular diseases: familial combined hyperlipidemia, hypoalphalipoproteinemia, hyperalphalipoproteinmia and normolipidemic controls. In addition, his lab investigates the impact of these same genetic variants on insulin resistance-related phenotypes, such as diabetes, obesity and non-alcoholic steatohepatitis. He teaches courses in genetics and genomics centered around: basic genomic science; the application of genomic risk assessment and testing; and pharmacogenetics, the application of genetically engineered therapeutic modalities.